Abstract
The sustainable development of natural polysaccharide-based hybrid composites is highly important for the effective replacement of metal nanoparticles in diverse applications. Here, polypyrrole nanotubes (PPyNTs) were embedded on the surface of aminated gum acacia (AGA) to produce ecofriendly nanocomposites for biomedical applications. The morphology of a PPyNT-enhanced AGA (PPyNT@AGA) hybrid nanocomposite was studied by scanning electron microscopy and transmission electron microscopy and their affirmed interactions were characterised by X-ray diffraction, Raman, Fourier transform-infrared and UV-visible spectroscopy. Interestingly, the prepared PPyNT@AGA nanocomposite exhibited 90% biofilm inhibition against gram-negative Pseudomonas aeruginosa, gram-positive Streptococcus pneumoniae and fungal strain Candida albicans with promising antimicrobial performance. This study establishes the good inhibition of a PPyNT@AGA hybrid composite against various microorganisms. The stability of the nanocomposite coupled with antimicrobial activity enables an effective strategy for diagnosing and controlling pathogens.