Human induced pluripotent stem cell line HMUi001-A derived from corneal stromal cells

源自角膜基质细胞的人类诱导性多能干细胞系 HMUi001-A

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作者:Timur Bikkuzin, Yan Shi, Baoqi Sun, Yiyuan Guo, Xin Jin, Zhenbo Han, Valentin Pavlov, Hong Zhang

Abstract

A human corneal stroma induced pluripotent stem cell (HMUi001-A) line was created from primary cultured human corneal fibroblasts. Reprogramming was performed using episomal vector delivery of OCT4, SOX2, KLF4, L-MYC and LIN28. Further characterization of the HMUi001-A confirmed that the cell line was pluripotent, free from Epstein Barr viral genome, and retained normal karyotype.

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