The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells

Notch配体DLL1在人类乳腺癌细胞中发挥致癌作用

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Abstract

These findings provide further evidence that DLL1 exerts carcinogenic effects in BC cells. The dissimilar effects of DLL1 downregulation observed amongst MCF-7, BT474, and MDA-MB-231 cells is likely due to their distinctive genetic and biologic characteristics, suggesting that DLL1 contributes to BC through various mechanisms.

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