Adult height and risk of coronary heart disease: Tehran Lipid and Glucose Study

成人身高与冠心病风险:德黑兰脂质和葡萄糖研究

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Abstract

BACKGROUND: We assessed the relationship between height and coronary heart disease (CHD) in an urban population of Tehran. METHODS: 4110 participants of the Tehran Lipid and Glucose Study who were 40 years of age or older (1880 men and 2230 women; mean age, 55.1 and 53.0 years, respectively) and free of CHD at baseline were followed for a mean of 9.1 years. We used Cox proportional hazards regression to evaluate the risk of a first CHD event across height tertiles. RESULTS: First CHD events occurred in 239 men and 172 women. The estimated crude HR (95% CI) for CHD events associated with an increment of 1 SD in height was 0.96 (0.28-3.33) in men and 0.84 (0.72-0.97) in women. After adjustment for age, the associations were no longer present. Further adjustment for other confounders had little impact on the results: the HR (95% CI) associated with an increase of 1 SD in height was 1.02 (0.87-1.20) in men and 0.82 (0.66-1.02) in women. CONCLUSIONS: After adjustment for age, height was not associated with CHD incidence in men or women.

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