Generation and characterization of induced pluripotent stem (iPS) cell line (SDUCTi001-A) using fibroblasts derived from male-healthy donor

使用来自男性健康供体的成纤维细胞生成和表征诱导性多能干细胞 (iPS) 系 (SDUCTi001-A)

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作者:Morad Kamand, Sonja Hohmann, Sheena Louise Forsberg, Mads Thomassen, Mirolyuba Ilieva, Åsa Fex Svenningsen, Morten Meyer, Tanja Maria Michel

Abstract

Induced pluripotent stem (iPS) cell lines have wide valuable applications in experimental research, including developmental, pathological, and drug screening studies. Using integration-free episomal plasmids, we have generated a new iPS cell line from a 26-year-old healthy male donor. Characterization of the established cell line confirmed the expression of pluripotency markers, differentiation into the three germ layers, and absence of chromosomal abnormalities.

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