How do early geriatric intervention and time to surgery influence each other in the management of proximal hip fractures?

在近端髋部骨折的治疗中,早期老年干预和手术时间如何相互影响?

阅读:1

Abstract

INTRODUCTION: Time to surgery (TTS) increases mortality risk in old patients with proximal femur fractures (PFFs). Orthogeriatric care pathways reduce mortality and length of stay, but the interaction between TTS and geriatric intervention remains unclear. OBJECTIVE: To identify organisational variables-including geriatric intervention-that are predictive of 90-day mortality and explore their interactions with TTS. MATERIALS AND METHODS: This retrospective study included 7756 PFFs aged over 60 who underwent surgery between 2005 and 2017. Organisational factors influencing 90-day mortality (main outcome) were identified in an administrative database using log-rank tests. Variables such as a mobile geriatric team (MGT) intervening in the emergency department were screened. Selected variables were included in a Cox model alongside TTS and the AtoG score, a validated multidimensional prognostic tool (from 0 no comorbidity to ≥5). Statistical interactions between TTS and organisational variables were calculated. RESULTS: MGT was one of the rare organisational variables with a protective effect: hazard ratio (HR) = 0.81, CI 95% [0.68-0.98], P = 0.03. MGT's strongest effect was for TTS up to 1 day (HR = 0.70, CI95% [0.53-0.92], P = 0.01) and then decreased beyond 2 days (HR = 0.97, CI95% [0.73-1.3], P = 0.08). In patients with an AtoG score ≤ 2, MGT was the strongest parameter: HR = 0.76, CI95% [0.60-0.93], P = 0.03, while the HR for TTS was 1.01 CI 95% [0.99; 1.02], P = 0.15. In patients with an AtoG>2, there was a synergic interaction between MGT and reduced TTS (P = 0.05). CONCLUSION: Geriatric intervention modulated the effect of TTS on 90-day mortality up to a TTS of 2 days. MGT had a positive impact on both vulnerable and earthier patients.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。