Abstract
INTRODUCTION: China, the world's largest tobacco market, has raised concerns due to e-cigarettes' health risks and rising youth usage. Despite a decade of regulatory policies, their effectiveness remains uncertain. This study examines trends in e-cigarette discourse on Weibo (2016-2025), analyzing discussion volume shifts and the impact of various topics on public engagement. METHODS: This study employs a hybrid computational approach integrating topic modeling, LLM-assisted annotation, and quantitative analysis to examine the evolution of e-cigarette discussions on Weibo (2015-2025) and topic dissemination effects (n=129769). LDA modeling identify 10 topics, followed by DeepSeek-V3-assisted classification. Linear regression in SPSS analyzed relationships between topic categories and social media engagement metrics (reposts/comments/likes) at 95% confidence intervals. RESULTS: Findings reveal 2020 as a key year of change: pro-vaping posts declined while anti-vaping content increased. Despite reduced volume, pro-vaping material maintained significant digital influence. Pre-policy, marketing content (p<0.01), health effects (p<0.01) and regulation (p<0.01) drove engagement. Post-policy, marketing lost engagement impact, while 'user experience' posts gained traction, significantly correlating with all interactions (all p<0.05). This indicates regulations were less effective against user-generated content, with pro-vaping messaging shifting towards peer-driven channels. Crucially, influencers consistently triggered strong engagement throughout the period (p<0.01) despite lower post volume, remaining key discourse drivers. CONCLUSIONS: Although China is strengthening its control over e-cigarettes, the results of our study indicate that this control remains limited. We advocate for more robust regulation of social media content, particularly concerning the management of celebrities and influencers, as well as the sharing of e-cigarette use experiences. However, the current regulatory framework enforced by the State Tobacco Monopoly Administration has proven inadequate for widespread and effective governance. We suggest that regulatory authority be shared with public health agencies in order to better integrate e-cigarette regulation with broader public health objectives.