Morphology-Preferable MoSe(2) Nanobrooms as a Sensing Platform for Highly Selective Apta-Capturing of Salmonella Bacteria

形貌优良的 MoSe(2) 纳米扫帚作为高选择性适体捕获沙门氏菌的传感平台

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Abstract

The present report employed nanobroom (NB)-shaped two-dimensional molybdenum diselenide (MoSe(2)) for the preparation of a sensing matrix for the detection of Salmonella paratyphi. An aptamer specific to salmonella was immobilized onto MoSe(2)NB-modified fluorine-doped tin oxide via glutaraldehyde cross-linking. Structural and morphological characterizations were performed using UV-vis spectroscopy, scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction techniques. Characterizations confirmed the nanobroom morphology and nanosize of the MoSe(2) material. Electrochemical studies revealed a good linear detection range of 10(-2)-10(-10) CFU/mL with low detection limit of 1 × 10(-10) CFU/mL and with R (2) = 0.98. The developed preferable nanobroom-shaped sensing matrix can provide a promising platform for rapid and accurate detection of Salmonella in real samples due to its tremendous stability and sensitivity.

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