Effects of induced electric field on the sensitivity of a two-compartment neuron model

感应电场对双室神经元模型敏感性的影响

阅读:1

Abstract

Sensitivity is one of the key characteristics of neurons in response to external stimuli. This study is based on a two-compartment Pinsky-Rinzel neuron model, which has been modified under the influence of a direct current induced electric field(DC-IEF). The research explores how this neuron model encodes stimuli from the DC-IEF, aiming to assess its sensitivity to firing in response to the induced electric field. Based on the two-compartment structural characteristics of the PR model neuron, the influence parameters of the model are altered under specific direct current stimulation to identify the state bifurcation points of the neuron at different parameters. At these bifurcation points, a DC-IEF is applied, and a planar graph is constructed to illustrate the relationship among firing rate, influence parameters, and electric field intensity. Through the analysis of the obtained data, it was found that PR neurons exhibit firing sensitivity to the DC-IEF. Furthermore, different influence parameters significantly affect their sensitivity and firing state.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。