Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy

甘露糖结合凝集素基因型与婴儿期对EB病毒感染的易感性

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Abstract

In a cohort study of children < 4 years of age in Greenland, mannose-binding lectin (MBL2) genotypes and Epstein-Barr virus (EBV) antibody levels were determined. EBV seropositivity was significantly lower and time to seroconversion increased in MBL-insufficient compared with MBL-sufficient children, indicating that MBL may be involved in primary EBV infection in infancy.

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