Discovery of a potent and selective cell division cycle 7 inhibitor from 6-(3-fluoropyridin-4-yl)thieno[3,2-d]pyrimidin-4(3H)-one derivatives as an orally active antitumor agent

从6-(3-氟吡啶-4-基)噻吩并[3,2-d]嘧啶-4(3H)-酮衍生物中发现了一种高效且选择性的细胞分裂周期7抑制剂，该抑制剂具有口服抗肿瘤活性。