Abstract
The One Health concept recognizes that the health of people is connected to the health of animals and the environment. A 21-year-old female patient presented with several nodular and cystic swellings on the front and sides of her neck for the past 2 years. Histopathology showed sulfur granules surrounded by neutrophils in an area of granulation tissue with filamentous Gram-negative bacilli in the granules. She was a regular cattle handler since her childhood, and one of her cows on the farm had died from a similar sort of illness 2 years back at the same period when her disease began. We made a provisional diagnosis of actinobacillus infection and started the patient on doxycycline 100 mg twice daily. With this treatment, the patient showed an excellent clinical response and her condition healed with resultant scarring within 7 weeks of treatment.