A Clinicohistopathological Analysis of Cutaneous Fibrous Histiocytomas of the Finger

手指皮肤纤维组织细胞瘤的临床病理分析

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Abstract

BACKGROUND: Cutaneous fibrous histiocytoma (CFH) is a common, benign skin tumor predominantly occurring on the extremities or trunk. However, CFH on the finger is rare. OBJECTIVE: This study was undertaken to examine the clinicohistopathological features of CFH of the finger. MATERIALS AND METHODS: This is a retrospective study of 12 CFHs located on fingers in a tertiary hospital in Korea. All case slides were retrieved from saved files. RESULTS: Ages of the CHF of the finger affected individuals ranged from 9 to 48 years with a male-to-female ratio of 1.4:1. Picker's nodule or wart was the most common clinical diagnosis. In only 2 out of the 12 cases was the pre-biopsy diagnosis of CFH ventured. Fibrocollagenous type was the most common histological type. Majority of the cases were mitotically inactive, exhibiting only 0-1 mitoses per high-power field and there was no recurrence. Tumor cells were uniformly CD34 negative. CONCLUSION: Because CFH can resemble malignancies including dermatofibrosarcoma protuberans, a lack of familiarity with the occurrence of CFH of the finger may lead to more aggressive treatment. Dermatologists should include CFH in their differential diagnosis of circumscribed nodules on the fingers to ensure proper management.

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