Elephantine Psoriasis with Papillomatosis and Alternating Hypogranulosis and Hypergranulosis

象皮状银屑病伴乳头状瘤病和交替性颗粒层减少与颗粒层增厚

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Abstract

Psoriasis is a disease of considerable clinical and histopathological diversity. We report a rare case of elephantine psoriasis responding very well to methotrexate. Histopathology revealed abnormal papillomatosis with finger-like projections in addition to alternating orthokeratosis with overlying hypergranulosis and parakeratosis with overlying hypogranulosis. We believe that this finding may represent an odd histopathologic type in elephantine psoriasis.

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