An uncontrolled open pilot study to assess the role of dietary eliminations in reducing the severity of atopic dermatitis in infants and children

一项非对照开放式试点研究,旨在评估饮食排除法在降低婴幼儿特应性皮炎严重程度方面的作用

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Abstract

BACKGROUND: The severity of atopic dermatitis (AD) has been reported to be reduced by dietary eliminations in a subset of patients with AD. AIMS: To assess the reduction of the severity of atopic dermatitis in infants and children after eliminations of certain dietary items. MATERIALS AND METHODS: The study group comprised of 100 children with atopic dermatitis. Their severity of itching, surface area of involvement, and SCORAD index were measured. Patients who did not have any systemic disease or were not on systemic corticosteroids were included in the study. Selected patients were advised to strictly adhere to a diet excluding milk and milk products, all kinds of nuts and nut-containing foods, egg and egg-containing foods, seafish and prawns, brinjal and soyabean for a period of 3 weeks. Instead of these avoided items, the food items to be included freely to maintain proper nutrition were dal and dal products, rohu fish, chicken, and fruits. All the preintervention parameters were measured again after 3 weeks. RESULTS: There was a statistically significant reduction in severity scores after dietary elimination alone. CONCLUSION: Dietary elimination helped to alleviate symptoms and signs in a subset of infants and children with AD.

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