Abstract
Leonurus has a long history of use in traditional Chinese medicine, particularly for its therapeutic effects in gynecological disorders and its ability to promote blood circulation. Leonurus contains a variety of bioactive compounds, including alkaloids, flavonoids, and terpenoids, which demonstrate significant pharmacological activities, such as antioxidant, anti-inflammatory, and neuroprotective effects. Additionally, combining Leonurus with conventional pharmaceutical treatments may produce synergistic effects, enhancing therapeutic outcomes. This review provides a comprehensive overview of the classification, distribution, traditional uses, and recent pharmacological advancements of Leonurus, with a particular focus on its potential applications in the treatment of brain diseases. It aims to deepen understanding of Leonurus's therapeutic potential in treating neurological conditions.