Chemotherapy-Induced Upregulation of Small Extracellular Vesicle-Associated PTX3 Accelerates Breast Cancer Metastasis

化疗诱导的小细胞外囊泡相关 PTX3 上调加速乳腺癌转移

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作者:Carson A Wills, Xiaoming Liu, Longgui Chen, Yuanjun Zhao, Christopher M Dower, Jeffrey Sundstrom, Hong-Gang Wang

Significance

These findings show that chemotherapy-induced small extracellular vesicles accelerate breast cancer metastasis, and targeted inhibition of tumor-derived vesicles may be a promising therapeutic strategy to improve the efficacy of chemotherapy treatment.

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