Conclusion
This study describes norovirus-specific serological responses in a child with four consecutive norovirus infection during the first 2 years of life. The response is type-specific and does not protect from a subsequent infection with a heterologous virus. What is known: • Correlates of protection to norovirus infection and disease are not yet determined, and most of the presently available data concern adult population. What is new: • This manuscript describes serological immune responses after primary and subsequent infections in a child during the first 2 years of life.