Site-agnostic PARP-inhibitor maintenance therapy of advanced stage BRCA2-mutated gastric-type endocervical adenocarcinoma: A case report

晚期BRCA2突变型胃型宫颈腺癌的部位非特异性PARP抑制剂维持治疗:病例报告

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Abstract

• Gastric-type endocervical adenocarcinomas (GEA) are rare, aggressive cancers with limited therapeutic options. • Although therapeutic effects of PARP-inhibitors in non-BRCA-associated cancers might be limited, clinical data is sparse. • Given limited treatment options and poor prognosis of GEA, somatic BRCA mutation testing, and PARP-inhibitor maintenance can be considered.

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