Taking the next step in PARP-inhibitor clinical trials in older women with ovarian cancer - Staging the aging

针对老年卵巢癌女性的PARP抑制剂临床试验进入下一阶段——衰老分期

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Abstract

•Older patients are still underrepresented in randomized controlled clinical trials.•Older patients receiving PARP-inhibitors tend to achieve shorter PFS, even those considered fit.•Older patients experience more side effects, than their younger counterparts.•Prospective "real-world" data is needed in unselected older women with ovarian cancer receiving PARP-inhibitors.

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