A Case Report of Severe Rhabdomyolysis Following Parathyroidectomy: A Likely Synergistic Effect of Statins and General Anaesthetics

甲状旁腺切除术后严重横纹肌溶解症病例报告:他汀类药物和全身麻醉剂可能存在协同作用

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Abstract

Rhabdomyolysis is caused by the disintegration of skeletal muscle fibres, leading to the release of toxic intracellular components into the systemic circulation resulting from direct or indirect injury to skeletal muscle, and has potential life-threatening complications such as acute renal failure. Drug-induced rhabdomyolysis, a significant subset of this syndrome, is often idiosyncratic in nature, making it challenging to study and predict. Our report explores a case of severe rhabdomyolysis following uncomplicated general anaesthesia for parathyroidectomy in a patient who was on statin therapy perioperatively for 14 years and had relatively no side effects arising from it.

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