Expression and function of kisspeptin during mouse decidualization

kisspeptin 在小鼠蜕膜化过程中的表达及作用

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作者:Peng Zhang, Min Tang, Ting Zhong, Yan Lin, Teng Zong, Chengxue Zhong, BaoPing Zhang, Min Ren, HaiBin Kuang

Background

Plasma kisspeptin levels dramatically increased during the first trimester of human pregnancy, which is similar to pregnancy specific glycoprotein-human chorionic gonadotropin. However, its particular role in the implantation and decidualization has not been fully unraveled. Here, the study was conducted to investigate the expression and function of kisspeptin in mouse uterus during early pregnancy and decidualization. Methodology/principal findings: Quantitative PCR

Conclusion

our results demonstrated that Kiss1/GPR54 system was involved in promoting uterine decidualization during early pregnancy in mice.

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