Abstract
This article presents an overview of research aimed at developing a scientific approach to creating multisensor optical systems for chemical analysis. The review is mainly based on the author's works accomplished over the recent 10 years at Samara State Technical University with broad international cooperation. It consists of an introduction and five sections that describe state of the art in the field of optical sensing, suggested development methodology of optical multisensor systems, related aspects of experimental design and process analytical technology followed by a collection of practical examples in different application fields: food and pharmaceutical production, medical diagnostics, and ecological monitoring. The conclusion summarizes trends and prospects of the multisensory approach to optical spectral analysis.