Neurotropism of mouse-adapted haemagglutinating encephalomyelitis virus

小鼠适应性血凝性脑脊髓炎病毒的嗜神经性

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Abstract

The propagation of a mouse-adapted strain (67N) of haemagglutinating encephalomyelitis virus in infected mice and murine cells was examined by viral re-isolation and immunostaining. Viral propagation was strictly limited to the neurons and to an established line of neuroblastoma cells in in-vivo and in-vitro experiments. These results provide adequate evidence that this virus is neurotropic.

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