Antimicrobial and Morphological Effect of Er,Cr:YSGG Laser Irradiation on Primary Dentine Infected by Microorganisms Associated With Early Childhood Caries

Er,Cr:YSGG激光照射对感染早期儿童龋病相关微生物的乳牙本质的抗菌和形态学影响

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Abstract

PURPOSE: Laser technology enables a less stressful lesion removal with antimicrobial effects, this study was addressed to evaluate the antimicrobial and morphological effect of Erbium, Chromium: Yttrium-Scandium-Gallium-Garnet (Er,Cr:YSGG) laser on infected primary dentine with Lactobacillus spp. and Candida albicans. MATERIALS AND METHODS: In-vitro experimental study, where 35 samples of primary dentine were randomly distributed into 5 groups (n = 7): 3 controls (non-irradiated G1_C, G2_LB and G3_CA) and 2 experimental (G4_LB+Er,Cr:YSGG and G5_CA+Er,Cr:YSGG). The samples were placed in culture media pre-inoculated with Lactobacillus spp. and C. albicans, according to the experimental group, and maintained under optimal temperature and sterility conditions; then groups G4_LB+Er,Cr:YSGG and G5_CA+Er,Cr:YSGG were irradiated with Er,Cr:YSGG laser at 4.5 w, 15 Hz, 1 s/mm2 (H mode) and 53.6 J/cm2. Subsequently, they were transferred to sterile culture media, and microbial colony-forming units (CFUs) were performed in triplicate after 24 h using serial dilutions. The adherent bacteria and morphology of primary dentine were observed with scanning electron microscopy (SEM). RESULTS: There were significant differences among control groups (G2_LB and G3_CA) and experimental (G4_LB+Er,Cr:YSGG and G5_CA+Er,Cr:YSGG) groups (P 0.001); additionally, the percentage reduction after laser treatment was 99% for group G4_LB+Er,Cr:YSGG and 98% for G5_CA+Er,Cr:YSGG, indicating a significant reduction. On the other hand, samples irradiated with laser Er,Cr:YSGG [G4_LB + Er,Cr:YSGG], [G5_CA + ErCr:YSGG] showed an irregular surface with areas exhibiting micro-erosion and microcavities. CONCLUSIONS: Er,Cr:YSGG laser irradiation presented an antimicrobial effect against Lactobacillus spp. and C. albicans. Moreover, this procedure can alter the dentinal surface structure.

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