Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage

细胞周期蛋白D1沉默可抑制肿瘤发生，损害DNA双链断裂修复，从而使雄激素非依赖性前列腺癌细胞对DNA损伤更加敏感。