Circulating MiR-125b as a marker predicting chemoresistance in breast cancer

循环 MiR-125b 作为预测乳腺癌化疗耐药性的标志物

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作者:Hongjiang Wang, Guang Tan, Lei Dong, Lei Cheng, Kejun Li, Zhongyu Wang, Haifeng Luo

Background

Chemotherapy is an important component in the treatment paradigm for breast cancers. However, the resistance of cancer cells to chemotherapeutic agents frequently

Significance

These data suggest that circulating miR-125b expression is associated with chemotherapeutic resistance of breast cancer. This finding has important implications in the development of targeted therapeutics for overcoming chemotherapeutic resistance in novel anti-cancer strategies.

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