Circulating MiR-125b as a marker predicting chemoresistance in breast cancer

循环 MiR-125b 作为预测乳腺癌化疗耐药性的标志物

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Background

Chemotherapy is an important component in the treatment paradigm for breast cancers. However, the resistance of cancer cells to chemotherapeutic agents frequently

Significance

These data suggest that circulating miR-125b expression is associated with chemotherapeutic resistance of breast cancer. This finding has important implications in the development of targeted therapeutics for overcoming chemotherapeutic resistance in novel anti-cancer strategies.

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