Abstract
The trans-tetrafluoro-λ(6)-sulfane (SF(4)) group has been utilized as a unique three-dimensional building block for the linear connection of two independent N-heterocycles, pyridines and triazoles. The linearly connected heterocyclic compounds were synthesized by thermal Huisgen 1,3-dipolar cycloaddition between previously unknown pyridine SF(4)-alkynes and readily available azides, providing a series of rod-like SF(4)-connected N-heterocycles in good to excellent yields. X-ray crystallographic analysis of the target products revealed the trans-geometry of the SF(4) group, which linearly connects two independent N-heterocycles. This research will open the field of chemistry of SF(4)-connected heterocyclic compounds.