Simple, one-step syntheses of tri- and tetracyclic B,N,S-heterocycles from reactions of a diboracumulene with thiols

通过二硼杂环戊烯与硫醇的反应,一步简便地合成三环和四环B,N,S杂环化合物

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Abstract

Boron-containing fused heterocycles have received considerable attention due to their unique structures, bonding, and intriguing properties. However, progress in this area has been hampered by a lack of efficient synthetic methodologies. In this study, we demonstrate the reactivity of a diboracumulene, LBBL (L = cyclic (alkyl)(amino)carbene, CAAC), with various nitrogen-containing heterocyclic thiols. These straightforward reactions result in the partial or complete cleavage of the B-B multiple bonds in the diboracumulene, along with S-H bond activation in the thiol units, leading to the formation of a range of tricyclic and tetracyclic B,N,S-heterocycles. Notably, the tricyclic B,N,S-heterocycle exhibits π aromaticity in all three of its rings.

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