Clinical case of endocarditis due to Trichosporon inkin and antifungal susceptibility profile of the organism

由毛孢子菌(Trichosporon inkin)引起的感染性心内膜炎的临床病例及其抗真菌药物敏感性分析

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Abstract

A fatal case of Trichosporon inkin prosthetic endocarditis is reported. The isolation sites and susceptibility profiles of 10 other isolates are also reviewed. Four strains were recovered from cutaneous or subcutaneous samples, four were recovered from urine, one was recovered from peritoneal liquid, and one was recovered from bone. Voriconazole and amphotericin B had the most potent activities in vitro against the isolates, with MIC geometric means of 0.11 and 0.30 microg/ml, respectively.

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