Abstract
The concurrent occurrence of invasive mold infections caused by two distinct fungal species in hematologic patients represents a rare and challenging condition. The mortality rate associated with these invasive fungal infections in neutropenic patients is high, underscoring the importance of timely diagnosis and prompt initiation of appropriate treatment to improve clinical outcomes. Herein, we present a concomitant acute invasive fungal rhinosinusitis (AIFR) and invasive pulmonary fungal infection caused by Aspergillus and Mucoraceae species in a patient with pre-B-cell acute lymphoblastic leukemia. This case highlights the need for further research to optimize outcomes in immunocompromised patients.