Mixed Candida albicans strain populations in colonized and infected mucosal tissues

定植和感染的黏膜组织中混合的白色念珠菌菌株群落

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Abstract

Multilocus sequence typing of six Candida albicans colonies from primary isolation plates revealed instances of colony-to-colony microvariation and carriage of two strain types in single oropharyngeal and vaginal samples. Higher rates of colony variation in commensal samples suggest selection of types from mixed populations either in the shift to pathogenicity or the response to antifungal treatment.

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