Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles

可见光促进的2H-吲唑C3-H直接氰甲基化反应

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Abstract

The efficient visible-light-promoted cyanomethylation of 2H-indazoles in the presence of Ir(ppy)(3) as the photocatalyst and bromoacetonitrile as the cyanomethyl radical source was achieved under mild conditions, providing a series of C3-cyanomethylated derivatives in good yields.

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