A human pluripotent stem cell line KUMi004-A generated from a patient with chronic lymphocytic leukemia

来自慢性淋巴细胞白血病患者的人类多能干细胞系 KUMi004-A

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作者:Ji-Hea Kim, Ka-Won Kang, Byung-Hyun Lee, Young Park, Hwa Jung Sung, Byung-Soo Kim

Abstract

Chronic lymphocytic leukemia (CLL) is a type of blood cancer caused by the abnormal accumulation of malignant plasma cells. In this study, we generated CLL iPSCs (KUMi004-a) using the Sendai virus, confirming pluripotency. Also, it can differentiate into three primary germ layers. We expect this cell line could be helpful to understand the pathology of CLL.

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