Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy

从患有免疫球蛋白 A 肾病的四岁男性患者的 PBMCs 中衍生出诱导性多能干细胞系 (GWCMCi001-A)

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作者:Xia Gao, Xin Liao, Jing Zhang, Jinai Lin, Mei Tan

Abstract

Immunoglobulin A nephropathy (IgAN) is a common primary glomerular disease contributing to end-stage renal failure. In this study, the induced pluripotent stem cell line GWCMCi001-A from PBMCs of a 4-year-old male patient with IgAN using the episomal plasmids was established, which is an ideal in vitro model to understand the exact pathogenesis of IgAN.

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