Derivation of an induced pluripotent stem cell line (GWCMCi001-A) from PBMCs of a four-year-old male patient with Immunoglobulin A nephropathy
从患有免疫球蛋白 A 肾病的四岁男性患者的 PBMCs 中衍生出诱导性多能干细胞系 (GWCMCi001-A)
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作者:Xia Gao, Xin Liao, Jing Zhang, Jinai Lin, Mei Tan
| 期刊: | Stem Cell Research | 影响因子: | 0.800 |
| 时间: | 2020 | 起止号: | 2020 Dec 10:50:102123. |
| doi: | 10.1016/j.scr.2020.102123 | 研究方向: | 发育与干细胞 |
| 细胞类型: | 干细胞 | |
Abstract
Immunoglobulin A nephropathy (IgAN) is a common primary glomerular disease contributing to end-stage renal failure. In this study, the induced pluripotent stem cell line GWCMCi001-A from PBMCs of a 4-year-old male patient with IgAN using the episomal plasmids was established, which is an ideal in vitro model to understand the exact pathogenesis of IgAN.
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