Abstract
Reports of near-death experiences (NDEs), end-of-life visions (ELVs), and culturally embedded afterlife narratives frequently describe profoundly positive or distressing states. Traditional interpretations treat these phenomena as evidence of external metaphysical realms. The Dying-Moment Dream Hypothesis proposes an alternative, neurobiologically grounded explanation: that culturally conditioned afterlife experiences may constitute a final, endogenous simulation ("dream") generated by the dying brain. This simulation is hypothesized to emerge from a confluence of transiently heightened terminal neural activity, affective-memory integration, temporal processing collapse, and the brain's neurochemical end-of-life cascade. Because subjective time may dilate under hypoxic stress, seconds of neural activity may be computationally experienced as a perceived loss of temporal boundaries. The absence of a subsequent awakening is proposed to render this final simulation the individual's last phenomenologically accessible conscious state. This paper synthesizes evidence from prospective NDE studies, terminal EEG recordings, dream neuroscience, cultural cognition, psychedelic research, and hospice ethnography to present a unified theoretical framework. Limitations, competing models, and explicitly falsifiable predictions are discussed.