Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
从无已知眼部疾病的健康捐赠者中生成两种人类对照 iPS 细胞系（UCLi016-A 和 UCLi017-A）
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作者：Cécile Méjécase, Philippa Harding, Hajrah Sarkar, Jonathan Eintracht, Dulce Lima Cunha, Lyes Toualbi, Mariya Moosajee
| 期刊： | Stem Cell Research | 影响因子： | 0.800 |
| 时间： | 2020 | 起止号： | 2020 Dec:49:102113. |
| doi： | 10.1016/j.scr.2020.102113 | 种属： | Human |
| 方法学： | FCM、IF、IHC-P | 靶点： | VIME |
| 研究方向： | 细胞生物学 | 细胞类型： | 其它细胞 |
Abstract
Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogramming. The established iPSC lines were found to express pluripotency markers, exhibit differentiation potential in vitro and display a normal karyotype. These cell lines will act as a control lines for researchers studying ocular diseases.
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