Recovery of the diffuse correlation spectroscopy data-type from speckle contrast measurements: towards low-cost, deep-tissue blood flow measurements

从散斑对比度测量中恢复漫相关光谱数据类型:迈向低成本深层组织血流测量

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Abstract

A multi-step Volterra integral equation-based algorithm was developed to measure the electric field auto-correlation function from multi-exposure speckle contrast data. This enabled us to derive an estimate of the full diffuse correlation spectroscopy data-type from a low-cost, camera-based system. This method is equally applicable for both single and multiple scattering field auto-correlation models. The feasibility of the system and method was verified using simulation studies, tissue mimicking phantoms and subsequently in in vivo experiments.

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