Abstract
Metal-Organic Frameworks (MOFs), as a new type of porous material, have attracted widespread attention in the fields of chemistry, materials science, and biomedicine owing to their unique structural characteristics and potential for functionalization. This review summarizes the latest research progress of MOFs in the field of steroid compounds, including the latest research progress of MOFs in the purification and separation of steroids, sensing and detection, catalytic transformation, and drug delivery. First, we explore how the porous structure and chemical functionalization of MOFs achieve efficient separation and purification of steroid compounds. Second, the high sensitivity and selectivity of MOFs as sensing materials in steroid detection, as well as their application potential in actual sample analysis, are analyzed. Furthermore, the role of MOFs in steroid catalytic transformation reactions is discussed, including their performance as catalysts or catalyst carriers. Finally, we focus on the innovative applications of MOFs in drug delivery systems, especially their advantages in controlled release and targeted drug delivery. This article also explores the future development trends and application prospects of MOFs in the field of steroids, highlighting the challenges and opportunities in material design, functionalization strategies, and practical implementations. Through this review, we aim to provide a comprehensive theoretical basis and practical guidance for further research and application of MOFs in the field of steroids.