Abstract
Neuromyelitis optica spectrum disorder (NMOSD) may mimic other neurological conditions, including multiple sclerosis (MS). We report a 25-year-old woman with hypothyroidism and depression who presented with progressive quadriparesis. Positive aquaporin-4 antibodies confirmed NMOSD. This case emphasizes the importance of considering NMOSD in patients with atypical demyelinating presentations and highlights the role of early diagnosis and targeted immunotherapy in improving outcomes.