Ultrahigh-resolution spectral domain optical coherence tomography with a blue-diode-pumped Ti:sapphire laser and an axicon lens

利用蓝光二极管泵浦钛蓝宝石激光器和锥透镜实现超高分辨率光谱域光学相干断层扫描

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Abstract

We present a novel, low-cost ultrahigh-resolution optical coherence tomography (OCT) system, based on a broadband blue-diode-pumped Kerr-lens mode-locked Ti:sapphire laser and an axicon lens to achieve high axial and lateral resolutions, respectively. With our spectral domain OCT system, we demonstrate a lateral resolution of < 3 µm and an axial resolution of 4.5 µm in air, corresponding to 3 µm resolution in biomedical tissue. Using this system, we present biomedical images of challenging biomedical tissues, namely highly transparent collagen hydrogel and opaque bone marrow.

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