Abstract
Photoacoustic imaging has demonstrated recent promise for surgical guidance, enabling visualization of tool tips during surgical and non-surgical interventions. To receive photoacoustic signals, most conventional transducers are rigid, while a flexible array is able to deform and provide complete contact on surfaces with different geometries. In this work, we present photoacoustic images acquired with a flexible array transducer in multiple concave shapes in phantom and ex vivo bovine liver experiments targeted toward interventional photoacoustic applications. We validate our image reconstruction equations for known sensor geometries with simulated data, and we provide empirical elevation field-of-view, target position, and image quality measurements. The elevation field-of-view was 6.08 mm at a depth of 4 cm and greater than 13 mm at a depth of 5 cm. The target depth agreement with ground truth ranged 98.35-99.69%. The mean lateral and axial target sizes when imaging 600 μm-core-diameter optical fibers inserted within the phantoms ranged 0.98-2.14 mm and 1.61-2.24 mm, respectively. The mean ± one standard deviation of lateral and axial target sizes when surrounded by liver tissue were 1.80±0.48 mm and 2.17±0.24 mm, respectively. Contrast, signal-to-noise, and generalized contrast-to-noise ratios ranged 6.92-24.42 dB, 46.50-67.51 dB, and 0.76-1, respectively, within the elevational field-of-view. Results establish the feasibility of implementing photoacoustic-guided surgery with a flexible array transducer.