Universal high-level primary metronidazole resistance in Helicobacter pylori isolated from children in Egypt

埃及儿童分离的幽门螺杆菌普遍存在高水平甲硝唑原发性耐药性

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Abstract

Antimicrobial susceptibility testing was performed on 48 isolates of Helicobacter pylori recovered from Egyptian children undergoing routine endoscopies. The isolates were universally highly resistant to metronidazole, but resistance to other tested antimicrobial agents was rare (4% for clarithromycin, erythromycin, and azithromycin resistance versus 2% for ciprofloxacin and ampicillin resistance). Use of metronidazole for the treatment of H. pylori in Egypt should be avoided.

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