Abstract
Oligonucleotides enriched in adenylate residues have been demonstrated in the genomes of two positive-strand RNA viruses, Sindbis and Columbia SK. Such oligonucleotides were not found in the genome of vesicular stomatitis virus, a negative-strand virus. The adenylate-rich oligonucleotides from Sindbis and Columbia SK viruses appeared similar when analyzed by zonal sedimentation in sucrose-sodium dodecyl sulfate.