Combined effect of furanone fluconazole and amphotericin B against biofilms formed from Cryptococcus neoformans

呋喃酮类药物氟康唑和两性霉素B联合作用对抗新型隐球菌生物膜

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Abstract

It is of interest to document the combined effect of furanone fluconazole and amphotericin B against the biofilm formed by Cryptococcus neoformans. The MIC values of amphotericine B and Fluconazole were observed as 20µg/ml and 60µg/ml, respectively. The MIC for the Combination (Amphotericin B/ Fluconazole) was found to be at (15/20) µg/ml drug concentration. Thus, data shows the combined effect of furanone fluconazole and amphotericine B derivative against C. neoformans.

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