Abstract
We describe a 30-year-old woman who had meningitis retention syndrome (MRS) with mild encephalitis/encephalopathy with a reversible splenial lesion (MERS), which occurred with fever, urinary retention, and weakness in both legs. A case of MRS with MERS is rare among adults, and its clinical course and treatment planning remain unknown. In the present, we highlighted the change in magnetic resonance imaging, blood tests, and cerebrospinal tests along with the treatment. A multidisciplinary approach by a radiologist and neurologist led to the diagnosis and appropriate treatment.