Plasma concentrations of soluble endoglin versus standard evaluation in patients with suspected preeclampsia
疑似先兆子痫患者的血浆可溶性内皮糖蛋白浓度与标准评估
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作者:Sarosh Rana, Ana Sofia Cerdeira, Julia Wenger, Saira Salahuddin, Kee-Hak Lim, Steven J Ralston, Ravi I Thadhani, S Ananth Karumanchi
| 期刊: | PLoS One | 影响因子: | 2.900 |
| 时间: | 2012 | 起止号: | 2012;7(10):e48259. |
| doi: | 10.1371/journal.pone.0048259 | 研究方向: | 信号转导 |
Conclusions
In women with suspected preeclampsia presenting prior to 34 weeks of gestation, sEng performs better than standard clinical evaluation in detecting adverse maternal and fetal outcomes occurring within two weeks of presentation. Soluble endoglin was strongly correlated with sFlt1 and PlGF levels, suggesting common pathogenic pathways leading to preeclampsia.
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