Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual
诱导性多能干细胞系 (PEIi003-A) 源自外表看似健康的男性个体
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作者:Nina V Fuchs, Maximilian Schieck, Michaela Neuenkirch, Christiane Tondera, Heike Schmitz, Doris Steinemann, Gudrun Göhring, Renate König
| 期刊: | Stem Cell Research | 影响因子: | 0.800 |
| 时间: | 2020 | 起止号: | 2020 Jan:42:101679. |
| doi: | 10.1016/j.scr.2019.101679 | 研究方向: | 发育与干细胞 |
| 细胞类型: | 干细胞 | |
Abstract
Induced pluripotent stem cells (iPSCs) are a useful tool to investigate pathomechanistic and cellular processes due to their differentiation potential into different somatic cell types in vitro. Here, we have generated iPSCs from an apparently healthy male individual using an integration-free reprogramming method. The resulting iPSCs are pluripotent and display a normal karyotype. Furthermore, we demonstrate that this iPSC line can be differentiated into all three germ layers.
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