Reply to Krupenko et al. Comment on "Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer Cancers 2020, 12, 1382"

回复 Krupenko 等人对“Lee 等人,《ALDH1L1 功能丧失与苯乙双胍治疗联合降低 KRAS 驱动的肺癌肿瘤生长》,Cancers 2020, 12, 1382”的评论

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Abstract

In the Cancers paper, we observed the increase ALDH1L1 protein expression following oncogenesis, as well as a therapeutic effect, by deleting the Aldh1l1 gene in Kras(LA2) mice, a model of spontaneous non-small cell lung cancer (NSCLC) [...].

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