Modulating immunometabolism of tumor specific mouse and human lymphocytes to enhance T cell based therapy for cancer

调节肿瘤特异性小鼠和人淋巴细胞的免疫代谢以增强基于T细胞的癌症治疗。

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Abstract

Sleep and metabolism are essential components of health. Metabolic health depends largely on individual's lifestyle. Disturbances in sleep health, such as changes in sleep patterns that are associated with menopause/reproductive aging and chronologic aging, may have metabolic health consequences. Sleep restriction and age-related changes in sleep and circadian rhythms may influence changes in appetite and reproductive hormones, energy expenditure, and body adiposity. In this article, the authors describe how menopause-related sleep disturbance may affect eating behavior patterns, immunometabolism, immunometabolic dysfunction, and associations between sleep and metabolic outcomes.

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